Eight individuals are being assessed by paramedics following the collision in Frankston about 1.45pm.
Police mentioned the crash has closed Cranbourne-Frankston Road close to the Peninsula Link in each instructions.
Police are directing site visitors on the closures and directing drivers to make use of McLelland Drive, Skye Road and Karingal Drive.
The Department of Transport has suggested drivers to keep away from the world the place doable and detour utilizing the Western Port Highway, Ballarto Road and Frankston-Dandenong Road.
Police mentioned the highway can be closed till investigations are full.
Source: www.9news.com.au