“These findings, using a completely new approach for targeting blood antibodies developed at Flinders University, indicate a common triggering factor on virus and vaccine structures that initiates the pathological PF4 antibodies,” the college’s Professor Tom Gordon mentioned.
“Indeed, the pathways of lethal antibody production in these disorders must be virtually identical and have similar genetic risk factors.”
The analysis comes after VITT emerged as a complication that occurred in some uncommon circumstances after receiving some COVID-19 vaccines, together with the Oxford-AstraZeneca jab utilized in Australia.
“VITT was found to be caused by an unusually dangerous blood autoantibody directed against a protein termed platelet factor 4 (or PF4),” Flinders University mentioned in an announcement.
Separately to analysis into the vaccine side-effect, specialists from North America and Europe final yr discovered an almost-identical blood illness with the identical PF4 antibody that was deadly for some individuals who had just lately had a typical chilly.
Flinders researchers Gordon and Dr Jing Jing Wang led a research in 2022 that “cracked the molecular code of the PF4 antibody and identified a genetic risk factor”, the college mentioned.
The newest COVID-19 pressure spreading internationally
The teams from Flinders University and abroad collaborated to search out the matching molecular fingerprints, publishing their findings within the New England Journal of Medicine at present.
Both Gordon and Wang mentioned the findings would play an essential position in enhancing vaccine security.
”Our findings have the important clinical implication that lessons learned from VITT are applicable to rare cases of blood clotting after adenovirus (a common cold) infections, as well as having implications for vaccine development,” Gordon mentioned.
Source: www.9news.com.au
