Aussie researchers make breakthrough IVF findings

“In our study, the overall live birth rate following frozen embryo transfer was 28 births per 100 people.

“If eggs have been collected in autumn, it was 26 births per 100 individuals, but when they have been collected in summer time there have been 31 births per 100 individuals.”

Leathersich said the birth rates for spring and winter lay between the two outlying figures and “weren’t statistically vital”.

The study also found a 28 per cent increase in the chances of a live birth when eggs were harvested on days with the most sunshine compared to those with the least.

“When we regarded particularly on the length of sunshine across the time the eggs have been collected, we noticed an identical improve to that seen for egg assortment throughout the summer time,” Leathersich said.

“The reside delivery fee following a frozen embryo switch from an egg that was collected on a day with fewer hours of sunshine was 25.8 per cent; this elevated to 30.4 per cent when the embryo got here from an egg that was collected on days with essentially the most hours of sunshine.

“When we took into account the season and conditions on the day of the embryo transfer, this improvement was still seen.”

The examine analysed 3657 frozen embryo transfers made at a Perth clinic between 2013 and 2021.

Leathersich stated that, by inspecting frozen eggs somewhat than recent transfers, he and his group have been in a position to isolate the impression of environmental components like sunshine within the success of an IVF delivery.

“It’s long been known that there is seasonal variation in natural birth rates around the world, but many factors could contribute to this including environmental, behavioural and sociological factors,” he stated.

“Most studies looking at IVF success rates have looked at fresh embryo transfers, where the embryo is put back within a week of the egg being collected.

“These days, many embryos are ‘frozen’ after which transferred at a later date.

“We realised this gave us an opportunity to explore the impact of environment on egg development and on early pregnancy separately by analysing the conditions at the time of egg collection independently from the conditions at the time of embryo transfer.”

Because the examine was retrospective, Leathersich stated additional analysis was warranted.

“Ideally, these findings should be replicated in other sites with different conditions and different treatment protocols to confirm the findings,” he stated.

“It would also be interesting to look at the impact of season and environmental factors on sperm parameters, as this could have contributed to our observations.”